Dosing And Administration

Qbrelis Offers Convenient Dosing and Administration

Ready-to-use lisinopril oral solution requires no additional preparation by the pharmacist or caregiver.
    Qbrelis is an oral solution containing lisinopril 1 mg/mL in 150 mL of aqueous solution with a sweet taste; no artificial flavoring or dyes.

FDA-Approved Dosing

Weight-based dosing for pediatric patients 6 years of age and older with hypertension
The recommended starting dose is 0.07 mg/kg (up to 5 mg orally total) once daily.
  • Dosage should be adjusted according to blood pressure response.
  • Doses above 0.61 mg/kg (or in excess of 40 mg) have not been studied in pediatric patients.
  • Qbrelis is not recommended in pediatric patients less than 6 years of age or in pediatric patients with glomerular filtration rate < 30 mL/min/1.73m2.

Dosing for adult hypertension
  • The recommended starting dosage is 10 mg orally once daily, up to a maximum of 40 mg daily based on blood pressure response.
  • The usual dosage range is 20 to 40mg per day.

  • Dosing for adults with cardiac conditions
    • For heart failure, initiate with 5 mg orally once daily, when used with diuretics and (usually) digitalis up to a maximum of 40 mg daily.
    • For acute myocardial infarction (MI), give 5 mg orally within 24 hours of MI, followed by 5 mg after 24 hours, then 10 mg once daily.

    Oral solution ensures consistent potency and stability
      • Same potency from first to last dose.
      • Consistent from hospital to home.
      • No refrigeration required—Qbrelis can be stored at room temperature (20°C–25°C, 68°F–77°F); in a tightly closed container. Protect from freezing and excessive heat.
      • No shaking necessary prior to administration.